Drug Name Erythromycin

Possible adverse effects are, with i.m.injection: persistent pain at the injection site and skin discoloration; with i.v. injection: flushing, hypotension, anaphylactic shock. Upon vascular injury, the coagulation system is activated: thrombocytes and fibrin molecules coalesce into a “plug” (p. 148) that seals the defect and halts bleeding (hemostasis).
To empty the urinary bladder (micturition), wall tension is increased by detrusor activation with a concurrent relaxation of sphincter tonus. Activation of ocular parasympathetic fibers (see below) results in narrowing of the pupil and increased curvature of the lens, enabling near objects to be brought into focus (accommodation).

This difference may be due to the higher impulse frequency and longer action potential duration in nociceptive, as opposed to motor, fibers. Alternatively, it may be related to the thickness of sensory and motor nerves, as well as to the distance between nodes of Ranvier. In saltatory impulse conduction, only the nodal membrane is depolarized.
Usually, chirality is due to a carbon atom (C) linked to four different substituents (“asymmetric center”). Enantiomerism is a special case of stereoisomerism. Nonchiral stereoisomers are called diastereomers (e. g. , quinidine/quinine). Bond lengths in enantiomers, but not in diastereomers, are the same.